Otsego Academy students participate in formal and informal activities with students from two area colleges, Colgate University and the State University of New York at Oneonta. Collaborative projects include education classes, seminars, special projects, clubs and social gatherings. Otsego Academy students access both college campuses and host activities at Pathfinder Village, too.

Spring semester at Otsego Academy features Leadership Week with students from Colgate University. Academy students complete team building, problem solving and leadership experiences with students participating in Colgate's Alternative Spring Break Program.